Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   F-Box Proteins 
Descriptor Spanish:   Proteínas F-Box 
Descriptor Portuguese:   Proteínas F-Box 
Synonyms English:   Domain Protein, F-Box
F Box Domain Protein
F Box Protein Family
F Box Proteins
F-Box Domain Protein
F-Box Protein Family
Protein Family, F-Box
Protein, F-Box Domain  
Tree Number:   D12.776.157.169
Definition English:   A family of proteins that share the F-BOX MOTIF and are involved in protein-protein interactions. They play an important role in process of protein ubiquition by associating with a variety of substrates and then associating into SCF UBIQUITIN LIGASE complexes. They are held in the ubiquitin-ligase complex via binding to SKP DOMAIN PROTEINS. 
See Related English:   F-Box Motifs
History Note English:   2004 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38252 
Unique Identifier:   D044783 

Occurrence in VHL: