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EPLERENONE
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DeCS
Descriptor
English
:
Eplerenone
Descriptor
Spanish
:
Eplerenona
Descriptor
Portuguese
:
Eplerenona
Synonyms
English
:
9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone
Eplerenon
Inspra
Tree Number:
D02.540.383
D04.210.500.745.745.329
Definition
English
:
A
spironolactone
derivative and selective
ALDOSTERONE
RECEPTOR antagonist that is used in the management of
HYPERTENSION
and CONGESTIVE
HEART FAILURE
, post-MYOCARDIAL
INFARCTION.
Pharmacological Action:
Mineralocorticoid Receptor Antagonists
Antihypertensive Agents
History Note
English
:
2019 (2000)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
57670
Unique Identifier:
D000077545
Occurrence in VHL
:
Similar:
DeCS