Search on: ENDOTHELINS 
Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   Endothelins 
Descriptor Spanish:   Endotelinas 
Descriptor Portuguese:   Endotelinas 
Synonyms English:   Endothelin
Endothelium-Derived Vasoconstrictor Factors
Vasoconstrictor Factors, Endothelium-Derived  
Tree Number:   D12.644.276.400
D12.776.467.400
D23.529.400
Definition English:   21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides. 
Indexing Annotation English:   GEN or unspecified; prefer specifics; /drug eff permitted
See Related English:   Receptors, Endothelin
 
History Note English:   91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   28921 
Unique Identifier:   D016232 

Occurrence in VHL:
 

Similar:

 
DeCS