Search on: ENDOTHELIN-3 
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Descriptor English:   Endothelin-3 
Descriptor Spanish:   Endotelina-3 
Descriptor Portuguese:   Endotelina-3 
Synonyms English:   Big Endothelin 3
Big Endothelin-3
Endothelin 3
Endothelin 3, Big
Endothelin-3, Big  
Tree Number:   D12.644.276.400.245
D12.776.467.400.245
D23.529.400.245
Definition English:   A 21-amino acid peptide that circulates in the plasma, but its source is not known. Endothelin-3 has been found in high concentrations in the brain and may regulate important functions in neurons and astrocytes, such as proliferation and development. It also is found throughout the gastrointestinal tract and in the lung and kidney. (N Eng J Med 1995;333(6):356-63) 
History Note English:   1997; use ENDOTHELINS 1991-1996; for BIG ENDOTHELIN 3 use ENDOTHELIN-3 (NM) 1993-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   33038 
Unique Identifier:   D019334 

Occurrence in VHL:
 

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