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DeCS
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Descriptor English:
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Endothelin-1
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Descriptor Spanish:
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Endotelina-1
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Descriptor Portuguese:
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Endotelina-1
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Synonyms English:
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Big Endothelin
Big Endothelin 1
Big Endothelin-1
Endothelin 1
Endothelin Type 1
Endothelin, Big
Endothelin-1, Big
Precursor, Proendothelin-1
Preproendothelin
Preproendothelin 1
Preproendothelin-1
Proendothelin (1-38)
Proendothelin 1 Precursor
Proendothelin-1 Precursor
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Tree Number:
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D12.644.276.400.225
D12.776.467.400.225
D23.529.400.225
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Definition English:
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A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63) |
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Indexing Annotation English:
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/drug eff permitted
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History Note English:
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2004(1997); use ENDOTHELINS 1991-96; for BIG ENDOTHELIN use ENDOTHELIN-1 (NM) 1990-2003; for PREPROENDOLTHELIN use ENDOTHELINS-1 (NM) 1989-2003
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Allowable Qualifiers English:
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Record Number:
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33036
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Unique Identifier:
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D019332
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Occurrence in VHL:
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Similar:
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DeCS
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