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EMETINE
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DeCS
Descriptor
English
:
Emetine
Descriptor
Spanish
:
Emetina
Descriptor
Portuguese
:
Emetina
Synonyms
English
:
Dihydrochloride, Emetine
Emetine Dihydrochloride
Emetine Hydrochloride
Hydrochloride, Emetine
Ipecine
Methylcephaeline
Tree Number:
D03.132.316
D03.633.100.531.321
Definition
English
:
The principal alkaloid of
ipecac
, from the ground roots of Uragoga (or
Cephaelis
)
ipecacuanha
or U. acuminata, of the
Rubiaceae
. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent
diarrhea
and
vomiting
.
Emetine
inhibits protein synthesis in
EUKARYOTIC CELLS
but not
PROKARYOTIC CELLS.
Pharmacological Action:
Amebicides
Antinematodal Agents
Cathartics
Emetics
Protein Synthesis Inhibitors
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
4715
Unique Identifier:
D004640
Occurrence in VHL
:
Similar:
DeCS