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Descriptor English:   Ethacrynic Acid 
Descriptor Spanish:   Ácido Etacrínico 
Descriptor Portuguese:   Ácido Etacrínico 
Synonyms English:   Acid, Etacrynic
Acid, Ethacrinic
Acid, Ethacrynic
Edecrin
Etacrynic Acid
Ethacrinic Acid
Ethacrynate Sodium
Ethacrynic Acid, Sodium Salt
Hydromedin
Sodium, Ethacrynate  
Tree Number:   D02.241.081.018.386.682.300
D02.241.511.316.682.200
Definition English:   A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic. 
Pharmacological Action:   Diuretics
Enzyme Inhibitors
 
History Note English:   66(63) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   5068 
Unique Identifier:   D004976 

Occurrence in VHL:
 

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DeCS