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DeCS
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Descriptor English:
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Epidermal Growth Factor
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Descriptor Spanish:
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Factor de Crecimiento Epidérmico
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Descriptor Portuguese:
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Fator de Crescimento Epidérmico
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Synonyms English:
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EGF
Epidermal Growth Factor-Urogastrone
Growth Factor, Epidermal
Growth Factor-Urogastrone, Epidermal
Human Urinary Gastric Inhibitor
Urogastrone
beta Urogastrone
beta-Urogastrone
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Tree Number:
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D06.472.317.350
D12.644.276.382.500
D12.776.467.382.500
D23.529.382.500
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Definition English:
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A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form. |
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See Related English:
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Anti-Ulcer Agents
ErbB Receptors
Gastrointestinal Agents
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History Note English:
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2000(1982); use PEPTIDES 1977-1981; for UROGASTRONE use GASTROINTESTINAL HORMONES 1963-1981
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Allowable Qualifiers English:
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Record Number:
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4896
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Unique Identifier:
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D004815
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Occurrence in VHL:
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Similar:
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DeCS
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