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DeCS
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Descriptor English:
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Down-Regulation
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Descriptor Spanish:
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Regulación hacia Abajo
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Descriptor Portuguese:
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Regulação para Baixo
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Synonyms English:
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Down Regulation
Down-Regulation (Physiology)
Down-Regulation, Receptor
Downregulation
Receptor Down-Regulation
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Tree Number:
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G02.111.240
G05.308.200
G07.690.773.937
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Definition English:
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A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. |
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See Related English:
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Feedback, Physiological
Up-Regulation
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History Note English:
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2002 (1990)
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Allowable Qualifiers English:
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Record Number:
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24611
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Unique Identifier:
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D015536
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Occurrence in VHL:
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Similar:
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DeCS
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