Search on: DIMETHYLALLYLTRANSTRANSFERASE 
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Descriptor English:   Dimethylallyltranstransferase 
Descriptor Spanish:   Dimetilaliltranstransferasa 
Descriptor Portuguese:   Dimetilaliltranstransferase 
Synonyms English:   Dimethylallyltransferase
Dolichyl Phosphate Synthetase
Geranylgeranyl Pyrophosphate Synthetase
Geranylpyrophosphate Synthetase
Nerylpyrophosphate Synthetase
Prenyltransferase
Synthetase, Geranylpyrophosphate
Synthetase, Nerylpyrophosphate  
Tree Number:   D08.811.913.225.400
Definition English:   An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1. 
History Note English:   97; was DIMETHYLALLYLTRANSFERASE 1979-96 (see under TRANSFERASES 1979-90) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   4170 
Unique Identifier:   D004122 

Occurrence in VHL:
 

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