Search on: DIHYDROERGOTOXINE 
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Descriptor English:   Dihydroergotoxine 
Descriptor Spanish:   Dihidroergotoxina 
Descriptor Portuguese:   Di-Hidroergotoxina 
Synonyms English:   Alkaloids, Hydrogenated Ergot
Co-Dergocrine
Dihydroergotoxin
Ergot Alkaloids, Hydrogenated
Hydrogenated Ergot Alkaloids  
Tree Number:   D03.132.327.412.250
D03.633.400.562.400
Definition English:   A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES. 
Pharmacological Action:   Adrenergic alpha-Antagonists
Dopamine Agonists
 
See Related English:   Dihydroergocornine
Dihydroergocristine
Dihydroergocryptine
 
History Note English:   1977(1975); for ERGOT ALKALOIDS, HYDROGENATED use ERGOLOID MESYLATES 1992-2001 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   4128 
Unique Identifier:   D004088 

Occurrence in VHL:
 

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