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DIGOXIN
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DeCS
Descriptor
English
:
Digoxin
Descriptor
Spanish
:
Digoxina
Descriptor
Portuguese
:
Digoxina
Synonyms
English
:
Boehringer, Digoxina
Digacin
Digitek
Digoregen
Digoxina Boehringer
Digoxine Nativelle
Dilanacin
Hemigoxine Nativelle
Lanacordin
Lanicor
Lanoxicaps
Lanoxin
Lanoxin PG
Lanoxin-PG
Lenoxin
Mapluxin
Nativelle, Digoxine
Nativelle, Hemigoxine
Tree Number:
D04.210.500.155.580.130.500.436
D04.210.500.155.580.130.688
D09.408.180.261.436
Definition
English
:
A cardiotonic glycoside obtained mainly from
Digitalis
lanata; it consists of three
sugars
and the aglycone
DIGOXIGENIN
.
Digoxin
has positive inotropic and negative chronotropic activity. It is used to
control
ventricular rate in
ATRIAL FIBRILLATION
and in the management of congestive
heart failure
with
atrial fibrillation
. Its use in congestive
heart failure
and sinus rhythm is less certain. The
margin
between toxic and therapeutic doses is small. (From Martindale, The Extra
Pharmacopoeia
, 30th ed, p666)
Indexing Annotation
English
:
do not confuse with
DIGITOXIN
Pharmacological Action:
Anti-Arrhythmia Agents
Cardiotonic Agents
Enzyme Inhibitors
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
4116
Unique Identifier:
D004077
Occurrence in VHL
:
Similar:
DeCS