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DEXTRORPHAN
Descriptors Found:
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DeCS
Descriptor
English
:
Dextrorphan
Descriptor
Spanish
:
Dextrorfano
Descriptor
Portuguese
:
Dextrorfano
Synonyms
English
:
(+-)-17-Methylmorphinan-3-ol
Tree Number:
D03.132.577.249.235
D03.605.497.260
D03.633.400.686.260
D04.615.723.795.235
Definition
English
:
Dextro form of
levorphanol
. It acts as a noncompetitive NMDA receptor antagonist, among other effects, and has been proposed as a neuroprotective agent. It is also a metabolite of
DEXTROMETHORPHAN.
Pharmacological Action:
Excitatory Amino Acid Antagonists
Neuroprotective Agents
History Note
English
:
91(75); was see under MORPHINANS 1975-90; DEXTRODROMORAN & D-DROMORAN were see DEXTRORPHAN 1977-94; DESTRORPHANOLUM was see DEXTRORPHAN 1975-94
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
3938
Unique Identifier:
D003917
Occurrence in VHL
:
Similar:
DeCS