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DeCS
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Descriptor English:
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Decitabine
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Descriptor Spanish:
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Decitabina
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Descriptor Portuguese:
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Decitabina
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Synonyms English:
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2' Deoxy 5 azacytidine
2'-Deoxy-5-azacytidine
5 Aza 2' deoxycytidine
5 Azadeoxycytidine
5 Deoxyazacytidine
5-Aza-2'-deoxycytidine
5-AzadC
5-Azadeoxycytidine
5-Deoxyazacytidine
5AzadC
AzadC Compound
Compound, AzadC
Dacogen
Decitabine Mesylate
Mesylate, Decitabine
NSC 127716
NSC-127716
NSC127716
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Tree Number:
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D02.145.150.500
D03.383.742.680.245.217.500
D13.570.685.245.217.500
D13.570.800.286.300.500
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Definition English:
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An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA. |
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Pharmacological Action:
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Antimetabolites, Antineoplastic
Enzyme Inhibitors
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See Related English:
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Cytarabine
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History Note English:
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2019 (1977)
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Allowable Qualifiers English:
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Record Number:
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57544
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Unique Identifier:
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D000077209
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Occurrence in VHL:
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Similar:
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DeCS
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