Search on: COLFORSIN 
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Descriptor English:   Colforsin 
Descriptor Spanish:   Colforsina 
Descriptor Portuguese:   Colforsina 
Synonyms English:   Coleonol
Forskolin
N,N-Dimethyl-beta-alanine-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl Ester HCl
NKH 477
NKH-477
NKH477  
Tree Number:   D02.455.849.291.300
Definition English:   Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant COLEUS FORSKOHLII. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland. 
Pharmacological Action:   Adjuvants, Immunologic
Bronchodilator Agents
Cardiotonic Agents
Vasodilator Agents
 
History Note English:   2014(1986) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   19578 
Unique Identifier:   D005576 

Occurrence in VHL:
 

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