Search on: CHROMOGRANINS 
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Descriptor English:   Chromogranins 
Descriptor Spanish:   Cromograninas 
Descriptor Portuguese:   Cromograninas 
Synonyms English:   Granins
Secretogranins  
Tree Number:   D12.776.631.199
D12.776.811.185
Definition English:   A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neuroendocrine cells. They play important roles in the aggregation, packaging, sorting, and processing of secretory protein prior to secretion. They are cleaved to release biologically active peptides. There are various types of granins, usually classified by their sources. 
History Note English:   1991(1973) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   2913 
Unique Identifier:   D002864 

Occurrence in VHL:
 

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