Search on: CATHEPSINS 
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Descriptor English:   Cathepsins 
Descriptor Spanish:   Catepsinas 
Descriptor Portuguese:   Catepsinas 
Synonyms English:   Cathepsin  
Tree Number:   D08.811.277.656.224
Definition English:   A group of lysosomal proteinases or endopeptidases found in aqueous extracts of a variety of animal tissues. They function optimally within an acidic pH range. The cathepsins occur as a variety of enzyme subtypes including SERINE PROTEASES; ASPARTIC PROTEINASES; and CYSTEINE PROTEASES. 
Indexing Annotation English:   note specifics
History Note English:   79; was CATHEPSIN 1963-78 (Prov 1963-64) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   2445 
Unique Identifier:   D002403 

Occurrence in VHL:
 

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