Search on: CATHELICIDINS 
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Descriptor English:   Cathelicidins 
Descriptor Spanish:   Catelicidinas 
Descriptor Portuguese:   Catelicidinas 
Tree Number:   D12.644.050.099
D12.776.543.695.054.099
Definition English:   Antimicrobial cationic peptides with a highly conserved amino terminal cathelin-like domain and a more variable carboxy terminal domain. They are initially synthesized as preproproteins and then cleaved. They are expressed in many tissues of humans and localized to EPITHELIAL CELLS. They kill nonviral pathogens by forming pores in membranes. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   52752 
Unique Identifier:   D054804 

Occurrence in VHL:
 

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