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CAPTOPRIL
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DeCS
Descriptor
English
:
Captopril
Descriptor
Spanish
:
Captopril
Descriptor
Portuguese
:
Captopril
Synonyms
English
:
(S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
Capoten
Lopirin
SQ 14,225
SQ 14,534
SQ 14225
SQ 14534
SQ-14,225
SQ-14,534
SQ-14225
SQ-14534
SQ14,225
SQ14,534
SQ14225
SQ14534
Tree Number:
D12.125.072.401.623.270
Definition
English
:
A potent and specific inhibitor of
PEPTIDYL-DIPEPTIDASE A
. It blocks the conversion of
ANGIOTENSIN I
to
ANGIOTENSIN II
, a vasoconstrictor and important regulator of arterial
blood pressure
.
Captopril
acts to suppress the
RENIN-ANGIOTENSIN SYSTEM
and inhibits
pressure
responses to exogenous
angiotensin.
Pharmacological Action:
Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
History Note
English
:
86(80); was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
23180
Unique Identifier:
D002216
Occurrence in VHL
:
Similar:
DeCS