Search on: CYP7 
Descriptors Found: 1
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Descriptor English:   Cholesterol 7-alpha-Hydroxylase 
Descriptor Spanish:   Colesterol 7-alfa-Hidroxilasa 
Descriptor Portuguese:   Colesterol 7-alfa-Hidroxilase 
Synonyms English:   CYP 7
CYP 7A
CYP7
CYP7A
Cholesterol 7 Hydroxylase
Cholesterol 7 alpha Hydroxylase
Cholesterol 7 alpha Monooxygenase
Cholesterol 7-alpha-Monooxygenase
Cholesterol 7alpha Hydroxylase
Cholesterol 7alpha-Hydroxylase
Cholesterol-7-Hydroxylase
Cytochrome P 450 CYP7
Cytochrome P-450 CYP7
Cytochrome P450 7  
Tree Number:   D08.244.453.890.500
D08.244.453.915.200
D08.811.682.690.708.170.890.500
D08.811.682.690.708.170.915.200
D12.776.422.220.453.890.500
D12.776.422.220.453.915.200
Definition English:   A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS. 
History Note English:   2003 (1975) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   23193 
Unique Identifier:   D002790 

Occurrence in VHL:
 

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