Search on: CYP3A 
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Descriptor English:   Cytochrome P-450 CYP3A 
Descriptor Spanish:   Citocromo P-450 CYP3A 
Descriptor Portuguese:   Citocromo P-450 CYP3A 
Synonyms English:   3A5, Cytochrome P450
6-alpha-Monooxygenase, Taurochenodeoxycholate
CYP3A
CYP3A4
CYP3A5
Cytochrome P 450 CYP3A
Cytochrome P 450 CYP3A4
Cytochrome P 450 CYP3A5
Cytochrome P 450IIIA
Cytochrome P-450 CYP3A4
Cytochrome P-450 CYP3A5
Cytochrome P-450IIIA
Cytochrome P450 3A
Cytochrome P450 3A4
Cytochrome P450 3A5
Erythromycin N Demethylase
Erythromycin N-Demethylase
N-Demethylase, Erythromycin
P-450 CYP3A, Cytochrome
P-450 CYP3A4, Cytochrome
P-450 CYP3A5, Cytochrome
P-450IIIA, Cytochrome
P450 3A, Cytochrome
P450 3A5, Cytochrome
Taurochenodeoxycholate 6 alpha Monooxygenase
Taurochenodeoxycholate 6-alpha-Monooxygenase  
Tree Number:   D08.244.453.860.500
D08.811.682.662.582.353
D08.811.682.690.708.170.495.500
D12.776.422.220.453.860.500
Definition English:   A cytochrome P-450 suptype that has specificity for a broad variety of lipophilic compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN. 
Entry Combination - descr/qualif English:   Cytochrome P-450 CYP3A/antagonists & inhibitors use Cytochrome P-450 CYP3A Inhibitors
 
History Note English:   2006(1980) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50572 
Unique Identifier:   D051544 

Occurrence in VHL:
 

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