Search on: CYP1A1 
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Descriptor English:   Cytochrome P-450 CYP1A1 
Descriptor Spanish:   Citocromo P-450 CYP1A1 
Descriptor Portuguese:   Citocromo P-450 CYP1A1 
Synonyms English:   7-Ethoxyresorufin O-Deethylase
CYP 1A1
CYP1A1
CYP1A1 Protein
Cytochrome P 450 CYP1A1
Cytochrome P450 IA1
EROD
Ethoxyresorufin Dealkylase
Ethoxyresorufin O-Deethylase
Ethylresorufin O-Deethylase  
Tree Number:   D08.244.453.005.332
D08.244.453.100.500
D08.811.682.690.708.170.010.277
D08.811.682.690.708.170.020.500
D12.776.422.220.453.010.332
D12.776.422.220.453.100.500
Definition English:   A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity. 
Indexing Annotation English:   do not confuse with other cytochrome P-450 CYP's
History Note English:   97; was ETHOXYRESORUFIN O-DEETHYLASE (NM) 1979-96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   33008 
Unique Identifier:   D019363 

Occurrence in VHL:
 

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