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CD4-IGG
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DeCS
Descriptor
English
:
CD4 Immunoadhesins
Descriptor
Spanish
:
Inmunoadhesinas CD4
Descriptor
Portuguese
:
Imunoadesinas CD4
Synonyms
English
:
CD4 IgG
CD4-IgG
Immunoadhesins, CD4
Tree Number:
D12.644.541.500.697.249
D12.776.124.486.485.538.500.249
D12.776.124.486.485.680.697.249
D12.776.124.790.651.538.500.249
D12.776.124.790.651.680.660.249
D12.776.377.715.548.538.500.249
D12.776.377.715.548.680.660.249
D12.776.395.550.200.230
D12.776.543.550.200.230
D12.776.828.300.200
D23.050.301.350.230
Definition
English
:
Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of
immunoglobulins
. These have potential use in the therapy of AIDS since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long
plasma
half-life
and Fc receptor-binding functions of immunoglobulin.
Pharmacological Action:
Immunologic Factors
History Note
English
:
92; was CD4 IMMUNOADHESIN (NM) 1989-91
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
30208
Unique Identifier:
D016860
Occurrence in VHL
:
Similar:
DeCS