Search on: CASP3 
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Descriptor English:   Caspase 3 
Descriptor Spanish:   Caspasa 3 
Descriptor Portuguese:   Caspase 3 
Synonyms English:   Apopain
CASP3
Caspase-3
Pro Caspase 3
Pro-Caspase-3
Procaspase 3
Procaspase-3  
Tree Number:   D08.811.277.656.262.500.126.350.300
D08.811.277.656.300.200.126.350.300
D12.644.360.075.405.350.300
D12.776.476.075.405.350.300
Definition English:   A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA. 
Entry Combination - descr/qualif English:   Caspase 3/antagonists & inhibitors use Caspase Inhibitors
 
History Note English:   2007(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52221 
Unique Identifier:   D053148 

Occurrence in VHL:
 

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