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BROMODEOXYURIDINE
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DeCS
Descriptor
English
:
Bromodeoxyuridine
Descriptor
Spanish
:
Bromodesoxiuridina
Descriptor
Portuguese
:
Bromodesoxiuridina
Synonyms
English
:
5 Bromo 2' deoxyuridine
5 Bromodeoxyuridine
5-Bromo-2'-deoxyuridine
5-Bromodeoxyuridine
BUdR
BrdU
Bromouracil Deoxyriboside
Broxuridine
Deoxyriboside, Bromouracil
NSC-38297
Tree Number:
D03.383.742.680.852.300.150
D13.570.230.430.196
D13.570.685.852.300.150
Definition
English
:
A nucleoside that substitutes for
thymidine
in DNA and thus acts as an antimetabolite. It causes breaks in
chromosomes
and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
Pharmacological Action:
Antimetabolites
Antimetabolites, Antineoplastic
Antiviral Agents
Radiation-Sensitizing Agents
History Note
English
:
66(65)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
2002
Unique Identifier:
D001973
Occurrence in VHL
:
Similar:
DeCS