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DeCS
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Descriptor English:
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Lymphocyte Activation
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Descriptor Spanish:
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Activación de Linfocitos
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Descriptor Portuguese:
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Ativação Linfocitária
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Synonyms English:
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Activation, Lymphocyte
Blast Transformation
Blastogenesis
Lymphoblast Transformation
Lymphocyte Stimulation
Lymphocyte Transformation
Stimulation, Lymphocyte
Transformation, Blast
Transformation, Lymphoblast
Transformation, Lymphocyte
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Tree Number:
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E01.370.225.812.482
E05.200.812.482
E05.478.594.530
G12.450.050.400.545
G12.565
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Definition English:
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Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION. |
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Indexing Annotation English:
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lymphocyte transformation test goes here but do not index under specific agent inducing transformation unless particularly discussed; do not use for neoplastic transformation of lymphocytes ( = CELL TRANSFORMATION, NEOPLASTIC) or viral transformation of lymphocytes ( = CELL TRANSFORMATION, VIRAL); blast transformation in chronic myelogenous leukemia does not go here: index BLAST CRISIS; DF: LYMPHOCYTE TRANSFORM
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See Related English:
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Blast Crisis
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History Note English:
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2003 (1969); for BLAST TRANSFORMATION use BLAST CRISIS 1987-1992
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Allowable Qualifiers English:
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Record Number:
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23302
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Unique Identifier:
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D008213
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Occurrence in VHL:
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Similar:
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DeCS
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