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BICUCULLINE
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DeCS
Descriptor
English
:
Bicuculline
Descriptor
Spanish
:
Bicuculina
Descriptor
Portuguese
:
Bicuculina
Synonyms
English
:
6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)furo(3,4-e)1,3-benzodioxol-8(6H)one
Tree Number:
D03.132.098.077
D03.633.100.531.085.077
Definition
English
:
An isoquinoline alkaloid obtained from
Dicentra
cucullaria and other
plants
. It is a competitive antagonist for GABA-A receptors.
Pharmacological Action:
Convulsants
GABA-A Receptor Antagonists
History Note
English
:
80(75); was see under ISOQUINOLINES 1975-79
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
1665
Unique Identifier:
D001640
Occurrence in VHL
:
Similar:
DeCS