Search on: B-518 
Descriptors Found: 1
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Descriptor English:   Cyclophosphamide 
Descriptor Spanish:   Ciclofosfamida 
Descriptor Portuguese:   Ciclofosfamida 
Synonyms English:   (+,-)-2-(bis(2-Chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-Oxide Monohydrate
B 518
B-518
B518
Cyclophosphamide Anhydrous
Cyclophosphamide Monohydrate
Cyclophosphamide, (R)-Isomer
Cyclophosphamide, (S)-Isomer
Cyclophosphane
Cytophosphan
Cytophosphane
Cytoxan
Endoxan
NSC 26271
NSC-26271
NSC26271
Neosar
Procytox
Sendoxan  
Tree Number:   D02.455.526.728.650.730.243
D02.705.672.500.243
Definition English:   Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. 
Pharmacological Action:   Immunosuppressive Agents
Mutagens
Antirheumatic Agents
Antineoplastic Agents, Alkylating
Myeloablative Agonists
 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   3540 
Unique Identifier:   D003520 

Occurrence in VHL:
 

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DeCS