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ATAXIN-3
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DeCS
Descriptor
English
:
Ataxin-3
Descriptor
Spanish
:
Ataxina-3
Descriptor
Portuguese
:
Ataxina-3
Synonyms
English
:
ATXN3 Protein
Ataxin 3
Ataxin 3 Protein
Ataxin-3 Protein
Machado Joseph Disease Protein
Machado-Joseph Disease Protein
SCA3 Protein
Spinocerebellar Ataxia 3 Protein
Tree Number:
D08.811.037.250
D12.776.631.069.875
D12.776.660.075.875
Definition
English
:
A deubiquitinating enzyme of the
ATAXINS
family
. It functions in protein
homeostasis
, GENETIC TRANSCRIPTION;
CYTOSKELETON
regulation, and MYOGENESIS. CAG
TRINUCLEOTIDE REPEAT EXPANSION
in the
Ataxin-3
gene coding region is associated with spinocerebellar ataxia-3 (
MACHADO-JOSEPH DISEASE
).
See Related
English
:
Spinocerebellar Ataxias
History Note
English
:
2016 (1995)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55958
Unique Identifier:
D000067699
Occurrence in VHL
:
Similar:
DeCS