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ANGIOTENSINOGEN
Descriptors Found:
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DeCS
Descriptor
English
:
Angiotensinogen
Descriptor
Spanish
:
Angiotensinógeno
Descriptor
Portuguese
:
Angiotensinogênio
Synonyms
English
:
Hypertensinogen
Proangiotensin
Renin Substrate
Renin Substrate Tetradecapeptide
Renin-Substrate
Serpin A8
Tetradecapeptide, Renin Substrate
Tree Number:
D12.644.456.073.070
D12.644.861.020
D12.776.811.070
D12.776.872.020
Definition
English
:
An alpha-globulin of about 453
amino acids
, depending on the species. It is produced by the liver and secreted into
blood circulation
.
Angiotensinogen
is the inactive precursor of natural
angiotensins
. Upon successive enzyme cleavages,
angiotensinogen
yields
angiotensin I
, II, and III with
amino acids
numbered at 10, 8, and 7, respectively.
Pharmacological Action:
Serine Proteinase Inhibitors
History Note
English
:
87(75); was see under ANGIOTENSINS 1975-86
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
27913
Unique Identifier:
D000808
Occurrence in VHL
:
Similar:
DeCS