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Descriptor English:   Ancrod 
Descriptor Spanish:   Ancrod 
Descriptor Portuguese:   Ancrod 
Synonyms English:   Agkistrodon Serine Proteinase
Agkistrodon rhodostoma Venom Protease
Arvin
Arvin IRC 50
Arvin IRC-50
Arvin IRC50
Arwin
Venacil  
Tree Number:   D08.811.277.656.300.760.955.060
D08.811.277.656.959.350.955.060
D20.888.850.960.200.050
D23.946.833.850.960.200.050
Definition English:   An enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy. EC 3.4.21.-. 
Pharmacological Action:   Anticoagulants
Fibrinolytic Agents
 
History Note English:   78; was ARVIN see under ENDOPEPTIDASES 1975-77; ARVIN was see ANCROD 1978-95 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   23155 
Unique Identifier:   D000721 

Occurrence in VHL:
 

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