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Descriptor English:   Complement Factor D 
Descriptor Spanish:   Factor D del Complemento 
Descriptor Portuguese:   Fator D do Complemento 
Synonyms English:   28 kDa Protein, Adipocyte
Activator, C3 Convertase
Adipsin
C3 Convertase Activator
C3 Proactivator Convertase
C3PA Convertase
C3PAse
Complement D Component
Complement Protein D
Convertase Activator, C3
Convertase, C3 Proactivator
Convertase, C3PA
Convertase, Proactivator
D Component of Complement
Factor D
Factor D, Complement
Factor D, Properdin
GBGase
Proactivator Convertase
Properdin Factor D
Protein D, Complement  
Tree Number:   D08.811.277.300.450
D08.811.277.656.300.760.200
D08.811.277.656.959.350.200
D12.776.124.486.274.045.450
Definition English:   A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE. 
Indexing Annotation English:   see SCR for organism-specific terms
Pharmacological Action:   Immunologic Factors
 
History Note English:   1999 (1978) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   23520 
Unique Identifier:   D011416 

Occurrence in VHL: 		 

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DeCS