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DeCS
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Descriptor English:
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Apolipoproteins E
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Descriptor Spanish:
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Apolipoproteínas E
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Descriptor Portuguese:
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Apolipoproteínas E
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Synonyms English:
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Apo E
Apo E Isoproteins
Apo-E
ApoE
Apolipoprotein E Isoproteins
Apoprotein (E)
Apoproteins E
Isoproteins, Apo E
Isoproteins, Apolipoprotein E
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Tree Number:
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D10.532.091.500
D12.776.070.400.500
D12.776.521.120.500
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Definition English:
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A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III. |
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History Note English:
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1985; for APOLIPOPROTEIN E ISOPROTEINS use APOLIPOPROTEINS E 1985-2006 & use APOLIPOPROTEINS 1983-1984
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Allowable Qualifiers English:
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Record Number:
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1063
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Unique Identifier:
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D001057
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Occurrence in VHL:
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Similar:
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DeCS
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