Search on: A-147627 
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Descriptor English:   Atrasentan 
Descriptor Spanish:   Atrasentán 
Descriptor Portuguese:   Atrasentana 
Synonyms English:   (11C)ABT-627
2-(4-Methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-1-(((dibutylamino)carbonyl)methyl)pyrrolidine-3-carboxylic acid
A 127722
A 127722.5
A 147627
A-127722
A-127722.5
A-147627
A127722
A127722.5
A147627
ABT 627
ABT-627
ABT627
Atrasentan Hydrochloride
Xinlay  
Tree Number:   D03.383.246.118.300
D03.383.773.079
D03.633.100.115.300
Definition English:   A pyrrolidine and benzodioxole derivative that acts a RECEPTOR, ENDOTHELIN A antagonist. It has therapeutic potential as an antineoplastic agent and for the treatment of DIABETIC NEPHROPATHIES. 
Pharmacological Action:   Antineoplastic Agents
Endothelin A Receptor Antagonists
 
History Note English:   2019 (1996) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   57771 
Unique Identifier:   D000077868 

Occurrence in VHL:
 

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