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DeCS
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Descriptor English:
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Irinotecan
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Descriptor Spanish:
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Irinotecán
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Descriptor Portuguese:
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Irinotecano
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Synonyms English:
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7 Ethyl 10 hydroxycamptothecin
7-Ethyl-10-hydroxycamptothecin
CPT 11
CPT-11
CPT11
Camptosar
Camptothecin 11
Camptothecin-11
Irinotecan Hydrochloride
Irrinotecan
NK012 Compound
SN 38
SN 38 11
SN-38
SN-38-11
SN3811
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Tree Number:
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D03.132.151.425
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Definition English:
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A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS. |
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Pharmacological Action:
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Topoisomerase I Inhibitors
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History Note English:
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2019 (1987)
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Allowable Qualifiers English:
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Record Number:
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57518
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Unique Identifier:
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D000077146
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Occurrence in VHL:
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Similar:
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DeCS
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