Search on: 5-OXOPROLYL-PEPTIDASE 
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Descriptor English:   Pyroglutamyl-Peptidase I 
Descriptor Spanish:   Piroglutamil-Peptidasa I 
Descriptor Portuguese:   Piroglutamil-Peptidase I 
Synonyms English:   5 Oxoprolyl Peptidase
5-Oxoprolyl-Peptidase
Aminopeptidase, Pyroglutamate
Peptidase, Pyrrolidonecarboxylate
Peptidase, Pyrrolidonyl
Pyroglutamate Aminopeptidase
Pyroglutamyl Peptidase I
Pyroglutamyl Peptide Hydrolase
Pyroglutamyl-Peptide Hydrolase
Pyrrolidonecarboxylate Peptidase
Pyrrolidonyl Peptidase  
Tree Number:   D08.811.277.656.350.100.755
Definition English:   An enzyme that catalyzes the release of a N-terminal pyroglutamyl group from a polypeptide provided the next residue is not proline. It is inhibited by thiol-blocking reagents and occurs in mammalian tissues, microorganisms, and plants. (From Enzyme Nomenclature, 1992) EC 3.4.19.3. 
History Note English:   95: was 5-OXOPROLYL-PEPTIDASE 1991-94; was PYROGLUTAMATE AMINOPEPTIDASE see under AMINOPEPTIDASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   29282 
Unique Identifier:   D011751 

Occurrence in VHL:
 

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