Search on:
2-METHYL-4-(4-METHYL-1-PIPERAZINYL)-10H-THIENO(2,3-B)(1,5)BENZODIAZEPINE
Descriptors Found:
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DeCS
Descriptor
English
:
Olanzapine
Descriptor
Spanish
:
Olanzapina
Descriptor
Portuguese
:
Olanzapina
Synonyms
English
:
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
LY 170052
LY 170053
LY-170052
LY170052
Olanzapine Pamoate
Zolafren
Zyprexa
Tree Number:
D03.633.100.079.080.738
Definition
English
:
A benzodiazepine derivative that binds
SEROTONIN
RECEPTORS; MUSCARINIC RECEPTORS;
HISTAMINE
H1 RECEPTORS; ADRENERGIC ALPHA-1 RECEPTORS; and
DOPAMINE
RECEPTORS. It is an antipsychotic agent used in the treatment of
SCHIZOPHRENIA
;
BIPOLAR DISORDER
; and MAJOR
DEPRESSIVE DISORDER
; it may also reduce
nausea
and
vomiting
in
patients
undergoing chemotherapy.
Pharmacological Action:
Antiemetics
Antipsychotic Agents
Serotonin Uptake Inhibitors
History Note
English
:
2019 (1992)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
57522
Unique Identifier:
D000077152
Occurrence in VHL
:
Similar:
DeCS