Search on: 2-METHOXYESTRADIOL 
Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   2-Methoxyestradiol 
Descriptor Spanish:   2-Metoxiestradiol 
Descriptor Portuguese:   2-Metoxiestradiol 
Synonyms English:   (17 beta)-2-methoxyestra-1,3,5(10)-triene-3,17-diol
2 Methoxyestradiol
2 Methoxyestradiol 17 beta
2 Methoxyoestradiol
2-(methyl-11C)Methoxyestradiol
2-Methoxyestradiol, (17alpha)-isomer
2-Methoxyestradiol-17 beta
2-Methoxyoestradiol
Panzem  
Tree Number:   D04.210.500.365.415.248.830
D06.472.334.851.437.500.750
Definition English:   A metabolite of estradiol that lacks estrogenic activity and inhibits TUBULIN polymerization. It has antineoplastic properties, including inhibition of angiogenesis and induction of APOPTOSIS. 
Pharmacological Action:   Antineoplastic Agents
Tubulin Modulators
 
History Note English:   2019 (1980) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   57692 
Unique Identifier:   D000077584 

Occurrence in VHL:
 

Similar:

 
DeCS