Search on: 2-CHLORO-11-(1-PIPERAZINYL)DIBENZ(B,F)(1,4)OXAZEPINE 
Descriptors Found: 1
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Descriptor English:   Amoxapine 
Descriptor Spanish:   Amoxapina 
Descriptor Portuguese:   Amoxapina 
Synonyms English:   2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine
Asendin
Asendis
CL 67,772
CL-67,772
CL67,772
Demolox
Desmethylloxapine
Défanyl  
Tree Number:   D03.633.300.347.500.040
Definition English:   The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression. 
Pharmacological Action:   Antidepressive Agents, Tricyclic
Neurotransmitter Uptake Inhibitors
Serotonin Uptake Inhibitors
Dopamine Antagonists
Adrenergic Uptake Inhibitors
 
History Note English:   91(75); was see under DIBENZOXAZEPINES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   672 
Unique Identifier:   D000657 

Occurrence in VHL:
 

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