Search on:
17-(3-PYRIDYL)-5,16-ANDROSTADIEN-3BETA-ACETATE
Descriptors Found:
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DeCS
Descriptor
English
:
Abiraterone Acetate
Descriptor
Spanish
:
Acetato de Abiraterona
Descriptor
Portuguese
:
Acetato de Abiraterona
Synonyms
English
:
17-(3-pyridyl)-5,16-androstadien-3beta-acetate
CB 7630
CB-7630
CB7630
Zytiga
Tree Number:
D04.210.500.054.079.065
Definition
English
:
An androstene derivative that inhibits
STEROID 17-ALPHA-HYDROXYLASE
and is used as an ANTINEOPLASTIC AGENT in the treatment of metastatic castration-resistant
PROSTATE
CANCER.
Pharmacological Action:
Antineoplastic Agents
Steroid Synthesis Inhibitors
Cytochrome P-450 Enzyme Inhibitors
History Note
English
:
2016 (1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
55939
Unique Identifier:
D000069501
Occurrence in VHL
:
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