Search on: (N-METHYL-11C)MIRTAZAPINE 
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Descriptor English:   Mirtazapine 
Descriptor Spanish:   Mirtazapina 
Descriptor Portuguese:   Mirtazapina 
Synonyms English:   (N-Methyl-11C)mirtazapine
(S)-Mirtazapine
6 Azamianserin
6-Azamianserin
Esmirtazapine
Norset
ORG 3770
ORG-3770
ORG3770
Org 50081
Remergil
Remeron
Rexer
Zispin  
Tree Number:   D03.633.300.240.588
Definition English:   A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders. 
Pharmacological Action:   Antidepressive Agents
Histamine H1 Antagonists
Anti-Anxiety Agents
Adrenergic alpha-2 Receptor Antagonists
Serotonin 5-HT2 Receptor Antagonists
Serotonin 5-HT3 Receptor Antagonists
 
History Note English:   2019 (1982) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   57855 
Unique Identifier:   D000078785 

Occurrence in VHL:
 

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