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MFN=57568
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DeCS
Descriptor
Inglés
:
Donepezil
Descriptor
Español
:
Donepezilo
Descriptor
Portugués
:
Donepezila
Sinónimos
Inglés
:
1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride
Aricept
Donepezil Hydrochloride
Donepezilium Oxalate Trihydrate
E 2020
E-2020
E2020
Eranz
Categoría:
D02.455.426.559.847.486.487.280
D03.383.621.238
D04.615.486.487.280
Definición
Inglés
:
An indan and piperidine derivative that acts as a selective and reversible inhibitor of
ACETYLCHOLINESTERASE
.
Donepezil
is highly selective for the
central nervous system
and is used in the management of mild to moderate
DEMENTIA
in
ALZHEIMER DISEASE.
Acción Farmacológica:
Cholinesterase Inhibitors
Nootropic Agents
Nota Histórica
Inglés
:
2019 (1992)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Número del Registro:
57568
Identificador Único:
D000077265
Ocurrencia en la BVS
:
Similar:
DeCS