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DeCS
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Descriptor Inglés:
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Serine Peptidase Inhibitor Kazal-Type 5
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Descriptor Español:
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Inhibidor de Serinpeptidasas Tipo Kazal-5
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Descriptor Portugués:
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Inibidor de Serinopeptidase do Tipo Kazal 5
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Sinónimos Inglés:
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Inhibitor, Lympho-Epithelial Kazal-Type
Kazal-Type Inhibitor, Lympho-Epithelial
LEKTI Protein
Lympho Epithelial Kazal Type Inhibitor
Lympho-Epithelial Kazal-Type Inhibitor
SPINK5 Protein
Serine Peptidase Inhibitor Kazal Type 5
Serine Protease Inhibitor Kazal Type 5
Serine Protease Inhibitor Kazal-Type 5
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Categoría:
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D12.644.822.750.250
D12.776.645.688.250
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Definición Inglés:
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A secreted serine peptidase inhibitor that consists of 15 KAZAL MOTIFS and inhibits KALLIKREINS KLK5, KLK7, and KLK14 as well as TRYPSIN. It plays important roles in protecting MUCOSA against infection and inflammation, and in maintaining the integrity of the skin. Mutations in the SPINK5 gene are associated with NETHERTON SYNDROME. |
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Relacionados Inglés:
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Kazal Motifs
Netherton Syndrome
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Nota Histórica Inglés:
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2018
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Calificadores Permitidos Inglés:
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Número del Registro:
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57063
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Identificador Único:
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D000074163
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Ocurrencia en la BVS:
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Similar:
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DeCS
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