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DeCS
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Descriptor Inglés:
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Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
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Descriptor Español:
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Proteína 1 de la Translocación del Linfoma del Tejido Linfático Asociado a Mucosas
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Descriptor Portugués:
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Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa
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Sinónimos Inglés:
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MALT 1 Protein
MALT-1 Protein
MALT1 Paracaspase
MALT1 Protein
Mucosa Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
Paracaspase
Paracaspase, MALT1
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Categoría:
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D08.811.277.656.262.500.126.775
D08.811.277.656.300.200.126.775
D08.811.464.938.750.233
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Definición Inglés:
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A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES. |
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Nota Histórica Inglés:
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2018
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Calificadores Permitidos Inglés:
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Número del Registro:
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57006
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Identificador Único:
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D000074884
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Ocurrencia en la BVS:
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Similar:
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DeCS
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