|
1 / 1
|
DeCS
|
|
 |
|
Descriptor Inglés:
|
|
Securin
|
|
Descriptor Español:
|
|
Securina
|
|
Descriptor Portugués:
|
|
Securina
|
|
Sinónimos Inglés:
|
|
PTTG Protein
Pituitary Tumor Transforming Proteins
Pituitary Tumor-Transforming Gene Protein
Pituitary Tumor-Transforming Proteins
|
|
Categoría:
|
|
D12.776.167.504
|
|
Definición Inglés:
|
|
Securin is involved in the control of the metaphase-anaphase transition during MITOSIS. It promotes the onset of anaphase by blocking SEPARASE function and preventing proteolysis of cohesin and separation of sister CHROMATIDS. Overexpression of securin is associated with NEOPLASTIC CELL TRANSFORMATION and tumor formation. |
|
Nota Histórica Inglés:
|
|
2014
|
|
Calificadores Permitidos Inglés:
|
|
|
|
Número del Registro:
|
|
55328
|
|
Identificador Único:
|
|
D064249
|
Ocurrencia en la BVS:
|
|
|
Similar:
|
|
DeCS
|