Expresión de búsqueda: ONCOSTATIN M 
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Descriptor Inglés:   Oncostatin M 
Descriptor Español:   Oncostatina M 
Descriptor Portugués:   Oncostatina M 
Categoría:   D12.644.276.374.562
D12.776.467.374.562
D23.529.374.562
Definición Inglés:   A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts. 
Acción Farmacológica:   Antineoplastic Agents
Growth Inhibitors
 
Nota Histórica Inglés:   2007(1987) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   52283 
Identificador Único:   D053683 

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