Expresión de búsqueda:
ECTODYSPLASINS
Descriptores Encontrados:
1
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DeCS
Descriptor
Inglés
:
Ectodysplasins
Descriptor
Español
:
Ectodisplasinas
Descriptor
Portugués
:
Ectodisplasinas
Sinónimos
Inglés
:
Ectodysplasin
Ectodysplasin A
Ectodysplasin A, Isoform 1
Ectodysplasin A, Isoform 2
Ectodysplasin A1
Ectodysplasin A2
Ectodysplasin-A
Categoría:
D12.644.276.374.750.186
D12.776.395.550.275
D12.776.467.374.750.186
D12.776.543.550.275
D23.529.374.750.186
Definición
Inglés
:
Transmembrane
proteins
belonging to the tumor
necrosis
factor superfamily that play an essential role in the normal development of several ectodermally derived organs. Several isoforms of the
ectodysplasins
exist due to multiple
ALTERNATIVE SPLICING
of the MRNA for the protein. The isoforms ectodysplasin A1 and ectodysplasin A2 are considered biologically active and each bind distinct ECTODYSPLASIN RECEPTORS. Genetic
mutations
that result in loss of function of ectodysplasin result in
ECTODERMAL DYSPLASIA
1, ANHIDROTIC.
Relacionados
Inglés
:
Ectodermal Dysplasia 1, Anhidrotic
Nota Histórica
Inglés
:
2007(1999)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52292
Identificador Único:
D053331
Ocurrencia en la BVS
:
Similar:
DeCS