Expresión de búsqueda:
APOPTOTIC PROTEASE-ACTIVATING FACTOR 1
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DeCS
Descriptor
Inglés
:
Apoptotic Protease-Activating Factor 1
Descriptor
Español
:
Factor Apoptótico 1 Activador de Proteasas
Descriptor
Portugués
:
Fator Apoptótico 1 Ativador de Proteases
Sinónimos
Inglés
:
Apaf 1 Protease Activating Factor
Apaf-1 Protease-Activating Factor
Apoptotic Peptidase Activating Factor 1
Apoptotic Protease Activating Factor 1
Protease-Activating Factor, Apaf-1
Categoría:
D12.644.360.024.131.124
D12.644.360.075.358.124
D12.776.157.057.006.124
D12.776.476.024.139.124
D12.776.476.075.358.124
Definición
Inglés
:
A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal
WD40 REPEATS
. It plays a role in the mitochondria-stimulated
apoptosis
(
APOPTOSIS
, INTRINSIC PATHWAY) and binds to
CYTOCHROME
C in the
CYTOSOL
to form an APOPTOSOMAL PROTEIN COMPLEX which activates
INITIATOR CASPASES
such as
CASPASE 9.
Nota Histórica
Inglés
:
2007(1997)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52304
Identificador Único:
D053477
Ocurrencia en la BVS
:
Similar:
DeCS