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DeCS
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Descriptor Inglés:
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Apolipoprotein E2
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Descriptor Español:
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Apolipoproteína E2
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Descriptor Portugués:
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Apolipoproteína E2
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Sinónimos Inglés:
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APOE epsilon 2
APOE epsilon2
APOE-epsilon 2
APOE-epsilon2
Apo E 2
Apo E-2
Apo E2
ApoE2
Apolipoprotein E 2
Apolipoprotein E epsilon2
Apolipoprotein E-2
Apolipoprotein E-epsilon2
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Categoría:
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D10.532.091.500.249
D12.776.070.400.500.249
D12.776.521.120.500.249
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Definición Inglés:
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One of three major isoforms of apolipoprotein E. In humans, Apo E2 differs from APOLIPOPROTEIN E3 at one residue 158 where arginine is replaced by cysteine (R158--C). In contrast to Apo E3, Apo E2 displays extremely low binding affinity for LDL receptors (RECEPTORS, LDL) which mediate the internalization and catabolism of lipoprotein particles in liver cells. ApoE2 allelic homozygosity is associated with HYPERLIPOPROTEINEMIA TYPE III. |
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Nota Histórica Inglés:
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2007 (1984)
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Calificadores Permitidos Inglés:
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Número del Registro:
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52266
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Identificador Único:
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D053329
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Ocurrencia en la BVS:
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Similar:
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DeCS
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