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Descriptor English:   p38 Mitogen-Activated Protein Kinases 
Descriptor Spanish:   Proteínas Quinasas p38 Activadas por Mitógenos 
Descriptor Portuguese:   Proteínas Quinases p38 Ativadas por Mitógeno 
Synonyms English:   MAP Kinase, p38
MAPK, p38
Mitogen Activated Protein Kinase p38
Mitogen-Activated Protein Kinase p38
Protein Kinase, p38
p38 MAP Kinase
p38 MAPK
p38 Mitogen Activated Protein Kinases
p38 Protein Kinase
p38 SAPK  
Tree Number:   D08.811.913.696.620.682.700.567.843
Definition English:   A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens. 
History Note English:   2005(1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38735 
Unique Identifier:   D048051 

Occurrence in VHL: